What is Amyotrophic Lateral Sclerosis?
Amyotrophic Lateral sclerosis also called as Lou Gehrig’s Disorder is rapidly progressive as well as fatal neurodegenerative disorder attacking motor nerve cells of the brain as well as spinal cord to destroy muscular movements of the human body. The literal meaning of the disease is the wastage of the voluntary muscles due to lack of their nourishments.
In fact, disease does not affect patient’s emotional or intelligence quotient, it is observed that a person may undergo a severe depression or alterations in the cognitive functions affecting memory or behaviour. Although, it has not been observed to affect the sensory neurons of the person maintaining his ability to touch, smell, taste, hear, etc.
FACTORS RESPONSIBLE FOR ALS
Although the exact cause of its occurrence is still unknown but different studies have revealed different facts about its occurrence such as genetic mutations or environmental exposure. Many of the other scientists have as well linked it up with unusual diet or injury.
The changes in the gene mutations can cause ALS, which has been confirmed by the National Institute of Neurological Disorder and stroke. The mutated gene that produces the enzyme SOD1 is found to be associated with the occurrence of the disease.
Some of the researchers have also linked it up with the toxic environmental factors such as lead exposure or infectious agents, as well as physical trauma or behavioral and occupational factors.
Neurons are the brain cells mainly located in the brain, spinal cord and the lower stem of the brain. These cells are known as the messengers connecting brain with the other parts of the body through spinal cord. They pass on the messages from brain to different organs of the body including voluntary muscles. These messages are passed on through signals from neurons to neurons.
Due to genetic mutations or environmental factors, if anything goes wrong with the passage of the information then the faulty information will be processed to the voluntary parts of the muscles due to which they observe a severe progressive degeneration. Due to lack of functional processing, the voluntary muscles of the body gradually weaken, waste away and have very fine twitches.
HOW STEM CELLS TREATMENT CAN HELP?
Stem cells are the mother cells that are responsible for developing an entire human body from a tiny two celled embryo; due to their unlimited divisions and strong power to differentiate into all the cells of different lineage. This power of stem cells has been harnessed by the technology to isolate them outside the human body, concentrate in the clean environment and implant back.
Thus stem cells treatment involves administration of concentrated cells in the targeted area, wherein they can colonize in the damaged area, adapt the properties of resident stem cells and initiate some of the lost functions that have been compromised by the disease or injury.
TREATMENT OF ALS
Treatment carefully and diligently follows the protocol as specified by GIOSTAR for ALS.
GIOSTAR have mastered the technology for isolating maximum number of viable stem cells from adipose tissue as an autologous source from your own body to treat ALS patients.
All GIOSTAR certified labs are well equipped state of the art facilities designed to isolate process and enrich the highest viable number of stem cells, which can be re infused back into the patient’s body. Generally, these cells are administered through any one of the below mentioned methods depending upon physical examination prior to administration:
- Intrathecal Administration:-Through this mode, cell are infused in the cerebrospinal fluid through the subarachnoid spaces of the spinal canal.
- Intravenous Administration:- Through this mode, cells are infused through the veins along with the mannitol to expand blood volumes in the central nervous system, to ensure that the maximum number of cells are reaching to the targeted area.
Once infused back in the body, these cells can be repopulated at the damaged areas of the brain and the spinal cord, through their strong paracrine effects and differentiate into lost neurons or other damaged supporting cells to improve voluntary functions of the body.
Thus with our standardized, broad based and holistic approach, it is now possible to obtain noticeable improvements in the ALS cases, in the symptoms as well as their functional abilities.
Results vary per patient and therapy is performed within the legal limits of the United States.